Molecular Genetics and Bioinformatics (BIO230)

The course gives an introduction to molecular genetics, gene regulation, cell cycle regulation, basic methods in gene technology and bioinformatics.


Course description for study year 2024-2025

Facts

Course code

BIO230

Version

1

Credits (ECTS)

10

Semester tution start

Autumn

Number of semesters

1

Exam semester

Autumn

Language of instruction

Norwegian

Offered by
Time table

View course schedule

Content

The course starts with the principles of classical genetics in view of our present understanding about cell division and the organization of chromosomes. The structure and organization of genes and mechanisms for gene expression will be covered. The most central methods in molecular genetics will be introduced, followed by lessons about gene regulation, genetic variation and cell cycle control. Modern methods for large scale studies of genomes and gene expression will be presented. Furthermore, defined defects in a cell's control mechanisms will be used to illustrate how these defects can lead to disease, as for example cancer. Finally, basic methods in bioinformatics will be introduced and used to solve problems.

Learning outcome

  • Understand how genes are assembled and the mechanisms for gene expression.
  • Know the principles of central gene technological methods and methods to map genomes, genetic variation and gene expression.
  • Understand the mechanisms for gene regulation both in prokaryotes and in eukaryotes.
  • Know the regulation of the cell cycle in relation to the development of cancer.
  • Have basic knowledge about bioinformatics.
  • Use web-based bioinformatics tools to solve problems

Required prerequisite knowledge

BIO100 Cell Biology, KJE150 General Chemistry

Recommended prerequisites

STA100 Probability and Statistics 1

Exam

Form of assessment Weight Duration Marks Aid
Written exam 1/1 4 Hours Letter grades None permitted

The exam is digital.

Coursework requirements

Two assignments
Two compulsory assignments must be approved in order to attend course examination.

Course teacher(s)

Course teacher:

Oddmund Nordgård

Course coordinator:

Oddmund Nordgård

Head of Department:

Ingunn Westvik Jolma

Method of work

Four hours lectures per week. Solving excercises with computer assistance.

Overlapping courses

Course Reduction (SP)
Gene technology (MOT190_1) 5
Introduction to Bioinformatics (BBI100_1) 5

Open for

Biological Chemistry - Biotechnology - Bachelor's Degree Programme Computer Science - Bachelor in Engineering Environmental Engineering - Bachelor in Engineering Environmental Engineering - Master of Science Degree Programme

Course assessment

There must be an early dialogue between the course supervisor, the student union representative and the students. The purpose is feedback from the students for changes and adjustments in the course for the current semester.In addition, a digital subject evaluation must be carried out at least every three years. Its purpose is to gather the students experiences with the course.

Literature

The syllabus can be found in Leganto